The outspoken journalist turned TV host is never afraid to speak his mind, launching scathing critiques of major names including Ariana Grande, British girl group Little Mix and the entire Kardashian Jenner clan (on multiple occasions).
But Morgan's latest rant was directed at two individuals who transcend global celebrity - namely Prince Harry and Meghan Markle.
WATCH: You won't believe what Piers Morgan said about Prince Harry!
The CNN anchor lashed out at the Duke and Duchess of Sussex on Good Morning Britain, criticising Harry for his much debated address and decision to bring his wife on stage at WE Day in London last Thursday.
The 53-year-old accused Meghan of stage managing the appearance and even writing the Duke's speech, before blasting Harry for a shift in his behaviour since marrying the former Suits actress.
Referring to the Prince's reported abstinence from alcohol during Meghan's pregnancy, Morgan raged: "I'm not being funny but what has happened to him? He can't have a drink, he can't even have caffeine, he's reading out this guff.
"I preferred him when he was playing naked billiards in Vegas, seriously."
The fiery wordsmith further declared dad-to-be Harry "doesn't have his own mind" and likened the son of Princess Diana to a robot.
Morgan's diatribe comes amid reports that Meghan is giving her husband acting lessons to help his confidence with public speaking.
The heavily pregnant Duchess allegedly hopes to boost the couples "star quality" by imparting some of her Hollywood expertise to the Prince.
The Sun's former royal editor Duncan Larcombe echoed Morgan's criticism of the Duke's Wembley address labelling it "stomach churning hippie talk".
Harry brought Meghan on stage to speak to a crowd of millennials, which Larcombe disdainfully described as a move that "wouldn't have looked out of place in some kind of fundraising dinner in Hollywood".