And true to form, the genetically blessed duo were in the presence of real life royalty as they joined Prince Charles for a dinner at Buckingham Palace on Tuesday night.
Human rights lawyer Amal looked like a contemporary Grecian goddess in a stunning white gown, which featured romantic draping and a statement asymmetric floor-length sleeve.
George, 57, was equally dapper in a black tie tuxedo.
The famous pair joined guests including Chiwetel Ejiofor, Benedict Cumberbatch and Tamsin Egerton for the gala reception in aid of the Prince of Wales' charity, Prince's Trust.
George and Amal, who are parents to toddler twins Ella and Alexander, looked at ease in royal company as they shared a joke with Prince Charles.
Amal, 41, shares a connection to the Windsors through her longtime friend and Charles' new daughter-in-law, Meghan Markle.
The Lebanese legal beauty and her husband attended Meghan and Harry's royal wedding in 2018 and reportedly hosted the Duke and Duchess of Sussex at their Lake Como villa last summer.
The heavily pregnant Duchess is said to have flown roundtrip on the Clooneys private jet for her lavish five day baby shower in New York last month.
Amal was seen arriving at Meghan's opulent accommodation alongside A-listers like Serena Williams, Jessica Mulroney and Abigail Spencer.