"The whole Cruise family got ordered back to LA when he divorced Nicole, as they were studying in Florida at the time," she added, which was when the indoctrination of hatred towards the Big Little Lies actress supposedly began.
Scientology whistleblower Tony Ortega told The Daily Beast: "Isabella and her brother Connor grew up in the Church of Scientology. Their mother, Nicole Kidman, was allegedly targeted by the Church because of their fear that she was turning her then-husband against them."
A similar situation occurred between Tom Cruise and his ex-wife Katie Holmes with their daughter, Suri Cruise.
"You can't be anti-Scientology if you're part of Tom's family, you will be disconnected - look at his daughter Suri," Ms Domingo said.
The Top Gun actor hasn't seen his daughter Suri since 2013, and has reportedly not reached out to her in any way since.
Ms Domingo initially kept quiet about the supposed indoctrination of hatred towards Nicole Kidman out of loyalty to the Cruise family.
However, it was the new Scientology promo featuring Cruise's daughter Isabella, 26, that inspired her to come forward.
She claimed that Isabella was being "used" as Scientology's "poster girl."
In the promo, Isabella thanked the Church and said, "This IS what I had been searching for. The missing piece. Suddenly everything began to make sense."
Ms Domingo claims the Church of Scientology is using Isabella to promote themselves.
"Isabella's being used for PR, she's Tom Cruise's kid, it's not fair what they're doing to her and Connor. They have no choice but to be the poster kids of Scientology now," the 51-year-old said.
WATCH: Nicole Kidman opens up about her children with Tom Cruise.
Ms Domingo is now out of the Church, along with her three daughters, and claims her story should serve as a cautionary tale about the dangers of Scientology.
A spokesperson for the Church of Scientology has denied Ms Domingo's claims, accusing her of lying at length about the Scientology religion, Daily Mail reports.