Earlier this year, the 53-year-old actress revealed that her husband 'annoyed' her and they are better off spending time apart.
'I know this sounds nuts, but we have lives that allow us to be away and come back together,' she admitted.
'His work life takes him here and mine takes me there,' Parker added, 'In some ways, I think that's been enormously beneficial.'
A source claims to Star that the couple's 21-year marriage could be on the rocks as a result of the couple's constant separation.
'Sarah and Matthew have been living separate lives for some time now,' a source spills to the publication, adding that the Hollywood couple even have separate homes.
'It could be a sign that they won't last much longer.'
Sarah and Matthew share three children - James Broderick, 15, and twin girls, Marion and Tabitha Broderick, 8.
Neither Sarah or Matthew have responded to Star's report.