Harry first visited the continent at a young age. When he was just 13 years old he met the Spice Girls in South Africa.
He also visited two months after his mother’s death in 1997.
Harry set up the charity ‘Sentebale’ when he was 21 in memory of his mother. Sentebale helps children and adolescents struggling to come to terms with their HIV status.
WATCH: Prince Harry talks moving to Africa
When Prince Harry was 24, and his brother William was 26, they both took part in a charity motorbike trek across South Africa.
In 2016, Harry assisted conservationists relocate African elephants to a safer home in Malawi.
"To actually get the chance to go to Africa, embed myself with the number one top vet in southern Africa, travel with him for three weeks and every job he gets called up to do, I follow him. That's like my dream,” Harry said.
Meghan and Harry took a 10-day trip to Africa as their first Royal tour.