The much-awaited coronial inquest will examine the circumstances surrounding the 2016 deaths of Kate Goodchild, her brother Luke Dorsett and his partner Roozi Araghi and Cindy Low, who were killed when a raft they were in on the Thunder River Rapids Ride malfunctioned and flipped.
Ms Goodchild's 12-year-old daughter Ebony and Ms Low's 10-year-old son survived.
Following the deaths, police investigated and have prepared a large brief of evidence for the coroner to consider.
They have already recommended no criminal charges be laid against Dreamworld staff over the fatal incident, but the coroner could still suggest prosecutions after hearing evidence.
Results of the inquest are expected to be released later in the year.