The Lion King premiere will be a significant moment for Prince Harry.
The screening will be held in support of his conservation work with The Royal Foundation, a joint charity initiative he shared with Prince William until late last week when Kensington Palace announced the Sussexes were exiting the project to pursue other philanthropic interests.
Buckingham Palace announced that the Duke of Sussex would attend the premiere last week and noted the Royal Foundation would be working with Disney's 'Protect the Pride'.
Since the original Lion King was released in 1994, half of Africa's lions have disappeared as a result of poaching and habitat destruction.
Prince Harry has been supportive of The Walt Disney Company's efforts to help protect Africa's lion population.
The Lion King is one of the Duke's favourite Disney films.
The film also holds sentimental value to the couple, who viewed the West End Stage Production on one of their dates in 2016.
Sir Elton John performed Circle of Life at Harry and Meghan's wedding reception at Windsor Castle last year.
Beyoncé is one of the stars in Jon Favreau's remake of The Lion King, playing the role of Nala.
The Grammy winner paid tribute to Meghan in her acceptance speech at the Brit Awards with her husband Jay Z last year.
The Carters made their speech in front of Tim O'Brien's portrait of the Duchess, and turned to face the portrait when their speech concluded.
Beyonce posted the photo featuring Meghan on Instagram afterwords, captioning it:
"In honor of Black History Month, we bow down to one of our Melanated Monas. Congrats on your pregnancy! We wish you so much joy."
The Lion King premiere is set to be a star-studded event full of friends and supporters of the royal couple.
It will no doubt be a special occasion for Prince Harry and Meghan.