Chezzi was speaking on the 2Day FM breakfast show her husband hosts alongside Ed Kavalee and Ash London.
Grant famously broke his back in a 2008 Monster Truck accident - which left him relying on medication to get by.
"The medication is often worse than the actual injury itself," Grant told the show. "The things it can do to your head...are so horrific.
"I could barely walk. I would wake up from a horrific dream and go and try and find my wife thinking there was a home invasion and thinking that she was being sexually attacked. I would crawl along the floor to try and fight off attackers that just weren't there," he said.
Chezzi broke down on air as she spoke of the ordeal.
"The things that he did and the things that I saw were really horrific," she said.
"I had to receive quite extensive counseling afterwards because he honestly believed he would never walk again and we had no real outside help. When we brought him home form hospital, I'm not a nurse, I didn't know what I was doing.
"Some of the things that we went through would test any relationship."